Cherry red spot is seen in all except

Correct Answer: Gaucher's disease
Description: D i.e. Gaucher's disease Cerry red spot at macula is seen in context of thickening and loss of transparency of retina at the posterior pole d/t accumulation of lipid (glycol/phospho) in ganglionic cell layer, giving the retina a white appearance. The fovea / foveola, being the thinnest pa of retina and devoid of ganglionic eels, retains relative transparency, allowing persistent transmission of underlying highly vascular choroidal hue. It is commonly seen in CRAO, Niemann-Pick disease, generalized gangliosidosis (GM1 gangliosidosis type 1), Tay-Sachs disease (GMlgangliosidosis type 1), Sandoff-disease (GM2 gangliosidosis type 2) and sialidosis type 1 and 2Q.
Category: Ophthalmology
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