Chemotherapeutic drugs can cause:
Correct Answer: Both necrosis and apoptosis
Description: Ans. is 'c' i.e., Both necrosis and apoptosis Chemotherapeutic drugs can cause both necrosis and apoptosis, but it is apoptosis which is the basis of action of chemotherapeutic drugs.Apoptosis is a process by which single cell are removed from the midst of living tissue by fragmentation into membrane bound particles and phagocytosed by other cells without disturbing its architecture or function or eliciting an inflammatory response (therefore known as programmed cell death).Though it is clearly written in Harrison that chemotherapeutic drugs can cause apoptosis and necrosis but its not clear whether necrosis has any role to play in therapeutic action.Also knowNecrosis - refers to cell death induced for example, by physical damage with the hallmark of cell swelling and membrane disruptionAnakusis - refers to death of epithelial cells after removal from the normal milieu of substrate, particularly from cell to cell contact.
Category:
Pathology
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