**Core Concept**
Peripheral chemoreceptors play a crucial role in detecting changes in the partial pressure of oxygen (pO2) and carbon dioxide (pCO2) in the blood. These receptors are primarily located in the carotid and aortic bodies and are sensitive to changes in the chemical composition of the blood.

**Why the Correct Answer is Right**
Peripheral chemoreceptors are stimulated by a decrease in pO2, an increase in pCO2, or an increase in hydrogen ion concentration (pH). This stimulation leads to an increase in the firing rate of the chemoreceptor neurons, which sends signals to the central nervous system to increase ventilation. **The correct answer is the one that does not trigger this response.**

**Why Each Wrong Option is Incorrect**
* **Option A:** Hypoxia (low pO2) stimulates peripheral chemoreceptors, so this is incorrect.
* **Option B:** Hypercapnia (high pCO2) stimulates peripheral chemoreceptors, so this is incorrect.
* **Option C:** Acidosis (low pH) stimulates peripheral chemoreceptors, so this is incorrect.

**Clinical Pearl / High-Yield Fact**
Peripheral chemoreceptors are not sensitive to changes in pO2 until it falls below a certain threshold (about 60 mmHg). This is why hyperventilation can lead to respiratory alkalosis, as the chemoreceptors are not stimulated to increase ventilation.

**Correct Answer: D. None of the above options do not stimulate peripheral chemoreceptors.**