**Core Concept**
Anti-phospholipid antibody syndrome (**APS**) is an autoimmune disorder characterized by the presence of anti-phospholipid antibodies, which are associated with **thrombosis** and **pregnancy complications**. The underlying mechanism involves the binding of these antibodies to **phospholipid-binding proteins**, leading to a **hypercoagulable state**.

**Why the Correct Answer is Right**
To determine the correct answer, we need to consider the typical features of APS, which include **venous or arterial thrombosis**, **recurrent fetal loss**, and **thrombocytopenia**. The correct answer should be a feature that is not typically associated with APS.

**Why Each Wrong Option is Incorrect**
**Option A:**
**Option B:**
**Option C:**
**Option D:**

**Clinical Pearl / High-Yield Fact**
A key point to remember is that APS can be **primary** (without any underlying disease) or **secondary** (associated with another condition, such as **Systemic Lupus Erythematosus**).

**Correct Answer:** D.