Characteristic feature of Goodpasture’s syndrome?
Correct Answer: Serum antibodies against alpha 3 NC 1 domain of collagen-IV
Description: In Goodpasture syndrome, type 1 RPGN & type II hypersensitivity reaction are seen. It is characterized by serum antibodies against alpha 3 NC1 domain of collagen - IV. Lumpy-bumpy deposits on immunofluorescence- seen in Post Streptococcal GN
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Pediatrics
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