Which is not a feature of cerebral malaria ?
**Core Concept**
Cerebral malaria is a complication of Plasmodium falciparum infection characterized by coma, seizures, and other neurological symptoms. It results from the sequestration of infected red blood cells in the cerebral microvasculature, leading to ischemia and inflammation.
**Why the Correct Answer is Right**
Cerebral malaria is typically associated with features such as coma, seizures, and altered mental status. The pathophysiology involves the sequestration of infected red blood cells in the cerebral microvasculature, which can lead to ischemia, inflammation, and ultimately, neurological symptoms. The parasite's ability to adhere to the endothelial lining of cerebral blood vessels contributes to its ability to cause cerebral malaria.
**Why Each Wrong Option is Incorrect**
**Option A:** Cerebral malaria can indeed cause fever, which is a common symptom of malaria. However, fever is not a specific feature of cerebral malaria.
**Option B:** Seizures are a common feature of cerebral malaria, making this option incorrect. Seizures can result from the inflammation and ischemia caused by the sequestration of infected red blood cells.
**Option C:** Cerebral malaria is a severe complication of malaria, and it can cause significant morbidity and mortality. This option is incorrect because it is a feature of cerebral malaria.
**Clinical Pearl / High-Yield Fact**
Cerebral malaria is a medical emergency that requires prompt recognition and treatment. The presence of coma, seizures, or altered mental status in a patient with malaria should raise suspicion for cerebral malaria.
**Correct Answer: A. Fever is not a specific feature of cerebral malaria.**