**Core Concept**
The cerebral cortex, particularly the primary somatosensory cortex (S1) and primary motor cortex (M1), plays a crucial role in processing sensory information from the body and controlling voluntary movements. After amputation, the brain's representation of the missing limb can lead to aberrant neural activity and perception, resulting in phantom limb pain.

**Why the Correct Answer is Right**
In individuals with phantom limb pain, PET scans often reveal increased activity in the contralateral cerebral cortex, specifically in the S1 and M1 areas corresponding to the missing limb. This hyperactivity is thought to be due to the brain's attempt to reorganize and compensate for the loss of sensory input from the missing limb. The preserved neural connections between the intact limb and the corresponding cortical areas can lead to cross-talk and aberrant activity, resulting in phantom sensations.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately describe the typical brain activity observed in individuals with phantom limb pain.
**Option B:** This option is incorrect because the statement is too vague and does not address the specific brain regions involved in phantom limb pain.
**Option C:** This option is incorrect because it suggests a decrease in activity, which is not consistent with the observed hyperactivity in the cerebral cortex of individuals with phantom limb pain.

**Clinical Pearl / High-Yield Fact**
Phantom limb pain is a classic example of central neuropathic pain, which can occur after nerve injury or amputation. Understanding the neural mechanisms underlying phantom limb pain can provide insights into the development of targeted treatments, such as cortical stimulation or pharmacological interventions.

**Correct Answer: C. Decreased activity in the contralateral cerebral cortex corresponding to the missing limb would not be expected in phantom limb pain.**

✓ Correct Answer: D. Projection of fibers from neighbouring sensory areas into the right hand area of his left somatic sensory area I