Central diabetes insipidus is characterised by-
Correct Answer: Low urine and high plasma osmolality
Description: Central diabetes insipidus is characterised by deficient production of ADH by the hypothalamus. In pituitary, gestational, or nephrogenic DI, there is polyuria (5-20 L or more in 24 hrs)and the urine is of low specific gravity and osmolality. The polyuria results in a small (1-2%) decrease in body water and a commensurate increase in plasma osmolarity and sodium that stimulates thirst and a compensatory increase in water intake. Thus in diabetes insipidus there is low osmolality of urine (below 600 mOsm/kg) in the presence of high plasma osmolality (greater than 300 mOsm/kg). The most common d/d is primary polydipsia where the urine is excessively dilute with low plasma osmolality. Reference : page 794 Davidson's Principles and practice of Medicine 22nd edition
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now