**Core Concept**
The question is testing the understanding of drugs that can induce Systemic Lupus Erythematosus (SLE), a chronic autoimmune disease characterized by the production of autoantibodies and immune complex deposition. Several medications have been associated with SLE-like reactions, and identifying these agents is crucial for clinicians.

**Why the Correct Answer is Right**
The correct answer is hydralazine, a vasodilator used in the treatment of hypertension. Hydralazine induces SLE-like reactions through an idiosyncratic immune-mediated mechanism, involving the formation of antinuclear antibodies (ANA) and the deposition of immune complexes. This reaction is thought to be mediated by the drug's ability to stimulate the production of interferon-gamma, which in turn activates T cells and promotes the production of autoantibodies.

**Why Each Wrong Option is Incorrect**
* **Option A:** Procainamide is an antiarrhythmic medication that can also induce SLE-like reactions, but it is not the correct answer in this case. Procainamide is associated with a higher risk of SLE-like reactions than hydralazine.
* **Option B:** Penicillin is an antibiotic that is not commonly associated with SLE-like reactions. While penicillin can cause a variety of hypersensitivity reactions, SLE-like reactions are not typically reported.
* **Option C:** This option appears to be blank. Please provide the actual options to complete the explanation.

**Clinical Pearl / High-Yield Fact**
It is essential for clinicians to be aware of the medications that can induce SLE-like reactions, as these reactions can be severe and potentially life-threatening. Patients taking medications associated with SLE-like reactions should be monitored closely for signs and symptoms of lupus, and alternative medications should be considered if necessary.

**Correct Answer: C. This option is not provided, please provide the correct answer to complete the explanation.