**Core Concept**
Acute rheumatic fever (ARF) is a complication of untreated or inadequately treated Group A beta-hemolytic streptococcal (GABHS) pharyngitis. The autoimmune response triggered by the infection leads to inflammation of the heart valves, joints, skin, and central nervous system.
**Why the Correct Answer is Right**
The cause of death in ARF is typically related to the cardiac complications, particularly rheumatic heart disease (RHD). RHD can lead to valvular dysfunction, most commonly mitral stenosis or regurgitation, which can cause heart failure, arrhythmias, or even sudden cardiac death. The inflammation of the heart valves, known as carditis, is the primary mechanism leading to these cardiac complications.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as there is no direct link between ARF and this cause of death.
**Option B:** While this is a potential complication of ARF, it is not the most common cause of death in these patients.
**Option C:** This is a potential cardiac complication of ARF but not the primary cause of death.
**Clinical Pearl / High-Yield Fact**
The Jones criteria, developed in 1944, are used to diagnose ARF. They consist of major and minor criteria, including carditis, polyarthritis, chorea, fever, and elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP). A diagnosis of ARF requires the presence of two major criteria or one major and two minor criteria.
**Correct Answer: D. Cardiac complications, particularly rheumatic heart disease (RHD).**
Free Medical MCQs · NEET PG · USMLE · AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.