Carey coombs murmur, which is false –
**Core Concept**
Carey Coombs murmur is a type of systolic ejection murmur that occurs due to the abnormal blood flow through the mitral valve, particularly in the context of a ventricular septal defect (VSD) with a small, anteriorly displaced mitral valve. This murmur is caused by the turbulent blood flow from the left ventricle into the left atrium through the mitral valve.
**Why the Correct Answer is Right**
Carey Coombs murmur is typically heard in the left parasternal area and is often associated with a VSD. The murmur is usually loudest at the apex and is best heard in early systole. The pathophysiology involves the abnormal blood flow through the mitral valve, which leads to the characteristic murmur. In the context of a VSD, the mitral valve is displaced anteriorly, which affects the flow of blood through the valve and results in the murmur.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because Carey Coombs murmur is indeed associated with VSD, and the murmur is caused by the abnormal blood flow through the mitral valve.
**Option B:** This option is incorrect because the characteristic location of Carey Coombs murmur is not the left lower sternal border, but rather the left parasternal area.
**Option C:** This option is incorrect because the timing of Carey Coombs murmur is early systole, not late systole.
**Clinical Pearl / High-Yield Fact**
Carey Coombs murmur is often associated with a VSD, and the murmur is an important diagnostic clue in the context of a small, anteriorly displaced mitral valve. The murmur is typically loudest at the apex and is best heard in early systole.
**Correct Answer: Not Given**
Since the correct answer was not provided, I will assume that the question is asking to identify the false statement among the options.