Cardiac conduction defect seen with Tricyclic antidepressants are due to-

Correct Answer: Both NE uptake inhibition and antimuscarinic action on hea
Description: Ans. is 'd' i.e., Both NE uptake inhibition and antimuscarinic action on hea o The commonest cardiovascular effect of tricyclic antidepressant overdose is sinus tachycardia, which is attributable to the inhibition of norepinephrine reuptake and the anticholinergic action.
Category: Pharmacology
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