Carcinoma of tongue most commonly occur at: March 2009
## **Core Concept**
Carcinoma of the tongue is a type of oral cancer that most commonly occurs on the lateral (side) surface of the tongue. This location is prone to malignant transformation due to various factors, including exposure to carcinogens and chronic irritation. The lateral surface, particularly the middle third of the tongue, is a common site for squamous cell carcinoma, which accounts for the majority of tongue cancers.
## **Why the Correct Answer is Right**
The correct answer, lateral surface of the tongue, is the most common site for carcinoma of the tongue because this area is more exposed to carcinogens present in tobacco and alcohol, which are major risk factors for oral cancer. Additionally, the lateral surface is more prone to chronic irritation and trauma, which can lead to malignant transformation. The lateral surface, especially the middle third, has a higher concentration of minor salivary glands and a thinner epithelial layer, making it more susceptible to cancer development.
## **Why Each Wrong Option is Incorrect**
* **Option A:** The tip of the tongue is not a common site for carcinoma of the tongue. While it can occur here, it's less common compared to the lateral surface.
* **Option B:** The dorsal (upper) surface of the tongue is not typically the most common site for carcinoma, as it is less exposed to direct carcinogens and irritants compared to the lateral surface.
* **Option D:** The base of the tongue, although it can be a site for cancer, is less common for squamous cell carcinoma compared to the lateral surface of the tongue. Cancers at the base of the tongue often present with nonspecific symptoms and are diagnosed at a later stage.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that cancers of the tongue are often associated with tobacco and alcohol use. Early detection is crucial, and any unexplained ulcer or swelling on the tongue should be biopsied. The lateral surface of the tongue is the most common site, making regular oral examinations critical for early detection.
## **Correct Answer:** C. Lateral surface of tongue