A patient comes with carcinoma cervix who has completed radiotherapy comes with uraemia. The most common cause is :
**Core Concept**
The underlying principle being tested is the understanding of complications arising from radiation therapy, particularly in the context of pelvic malignancies like carcinoma of the cervix. Radiation can cause damage to surrounding tissues and organs, including the urinary system. **Radiation nephropathy** and **ureteral obstruction** are potential complications.
**Why the Correct Answer is Right**
Since the options are not provided, let's discuss a common cause of uraemia in this context: ureteral obstruction. This can occur due to the tumor itself or as a result of radiation-induced fibrosis, leading to ureteral stricture. The mechanism involves the obstruction of urine flow, which can cause renal failure if not promptly addressed.
**Why Each Wrong Option is Incorrect**
Without specific options, it's challenging to address each incorrect choice directly. However, common incorrect options might include conditions less directly related to radiation therapy or carcinoma of the cervix, such as primary renal diseases or other causes of ureteral obstruction not related to the patient's cancer treatment.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that patients who have undergone pelvic radiation are at risk for **radiation-induced complications**, including those affecting the urinary system. Recognizing these potential complications early is crucial for timely intervention.
**Correct Answer:** D. Ureteric obstruction.