Call exner bodies is seen with :
**Core Concept**
Call-Exner bodies are distinctive histological features found in certain types of ovarian neoplasms, specifically granulosa cell tumors. These bodies are small, spherical or ovoid structures that consist of a central space surrounded by a ring of granulosa cells.
**Why the Correct Answer is Right**
Call-Exner bodies are characteristic of granulosa cell tumors due to their unique histological appearance. They are formed by the aggregation of granulosa cells around a central space, which may contain eosinophilic material or blood. The presence of Call-Exner bodies is a diagnostic feature that helps differentiate granulosa cell tumors from other types of ovarian neoplasms. The formation of these bodies is thought to be related to the abnormal growth and differentiation of granulosa cells.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because Call-Exner bodies are not typically associated with Brenner tumors, which are a type of transitional cell carcinoma of the ovary.
**Option B:** This option is incorrect because Call-Exner bodies are not characteristic of serous cystadenomas, which are a type of epithelial tumor that typically presents with a different histological appearance.
**Option C:** This option is incorrect because Call-Exner bodies are not typically associated with mucinous cystadenomas, which are a type of epithelial tumor that typically presents with a different histological appearance.
**Clinical Pearl / High-Yield Fact**
It's essential to recognize the histological features of granulosa cell tumors, including the presence of Call-Exner bodies, to make an accurate diagnosis and provide appropriate treatment.
**Correct Answer: D. Granulosa cell tumors**