Call exner bodies” are seen in :
**Question:** Call exner bodies are seen in:
A. Parietal cells in the stomach
B. Pancreas
C. Duodenal glands
D. Liver cells (hepatocytes)
**Core Concept:**
Call exner bodies, also known as Weil-Petersson granules or secretory granules, are specialized vesicles found within specific cells that contribute to the secretion of various substances. These granules are named after the scientists Oskar Exner and Carl Weil-Petersson who first described them. In this MCQ, we need to identify the cell type where Call exner bodies are found.
**Why the Correct Answer is Right:**
Call exner bodies are primarily observed in the stomach, specifically in the parietal cells (also known as chief cells). These cells are responsible for acid secretion in the gastric mucosa through the process of gastric acid secretion. The granules contain hydrogen ions (H+) which are released into the gastric lumen during the process of proton secretion.
**Why Each Wrong Option is Incorrect:**
A. Pancreas (option B) does not contain call exner bodies. The pancreas is responsible for the secretion of enzymes and hormones, not acid secretion.
B. Duodenal glands (option C) do not contain call exner bodies. Duodenal glands are involved in the secretion of digestive enzymes, not acid secretion.
D. Liver cells (option D) do not contain call exner bodies. Liver cells are involved in detoxification, bile secretion, and other physiological processes, but not acid secretion.
**Clinical Pearl:**
Understanding the location and function of Call exner bodies is essential for understanding gastric acid secretion and maintaining homeostasis. The presence of these granules in parietal cells allows for the regulation of gastric acid secretion, which is crucial for the proper functioning of the stomach and subsequent digestion in the small intestine.