Call-Exner bodies are seen in
## **Core Concept**
Call-Exner bodies are a histopathological feature associated with certain types of ovarian tumors. They are small, eosinophilic fluid-filled spaces or structures surrounded by rosettes of granulosa cells. This characteristic feature is particularly significant in the diagnosis of specific ovarian neoplasms.
## **Why the Correct Answer is Right**
The correct answer, **C. Granulosa cell tumor**, is associated with Call-Exner bodies because these tumors are known to produce these characteristic histological structures. Granulosa cell tumors are sex cord-stromal tumors that originate from the granulosa cells of the ovary. The presence of Call-Exner bodies, which are small, gland-like spaces surrounded by a rosette of granulosa cells, is a diagnostic hallmark of these tumors. This feature is crucial for the histopathological diagnosis of granulosa cell tumors.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because it does not correspond with the correct association of Call-Exner bodies.
- **Option B:** This option is incorrect as it does not accurately represent the type of tumor associated with Call-Exner bodies.
- **Option D:** This option is incorrect because it does not correctly identify the tumor type characterized by the presence of Call-Exner bodies.
## **Clinical Pearl / High-Yield Fact**
A key clinical pearl is that Call-Exner bodies are pathognomonic for granulosa cell tumors. These tumors are known for their estrogen-producing capabilities, which can lead to symptoms like endometrial hyperplasia or even endometrial cancer due to unopposed estrogen effects. Recognizing the histological features of these tumors is crucial for accurate diagnosis and management.
## **Correct Answer:** C. Granulosa cell tumor