Call exner bodies are seen in –
**Question:** Call exner bodies are seen in -
A. Parietal cells
B. Duodenal mucosa
C. Stomach mucosa
D. Pancreas
**Core Concept:**
Call exner bodies, also known as Paneth's granules, are specialized secretory granules found within the secretary cells of the gastrointestinal tract. These cells are primarily located in the submucosa layer of the stomach, small intestine, and appendix. In this context, the correct answer is:
**Correct Answer: C. Stomach mucosa**
**Why the Correct Answer is Right:**
Call exner bodies are essential components of the stomach's defense mechanism against pathogens. These granules contain various antimicrobial peptides and enzymes, such as lysozyme, chymotrypsinogen, and neutral proteases, which help neutralize and destroy harmful bacteria residing in the stomach's lumen.
**Why Each Wrong Option is Incorrect:**
A. Parietal cells are actually responsible for producing hydrochloric acid, not Call exner bodies. They are located in the chief cells of the stomach mucosa.
B. Duodenal mucosa is the correct answer for the pancreas because it houses the pancreatic acinar cells, which secrete digestive enzymes and bicarbonate ions. These substances are crucial for the digestion process in the small intestine, not associated with Call exner bodies.
D. Pancreas is incorrect because Call exner bodies are specific granules found in the gastrointestinal tract, while the pancreas primarily contains acinar cells and duct cells.
**Clinical Pearl:**
Understanding the location and function of Call exner bodies is essential for medical students and practicing physicians, as it directly relates to the defense mechanisms of the gastrointestinal tract and the importance of maintaining a healthy microbial balance in the stomach.