Calcium homeostasis is maintained by all except
Correct Answer: Lung
Description: Ans: b (lung)Ref: Ganong, 22nd ed. Pg. 392Kidney, liver and skin is related to the production of vitamin D in the body, so these are involved in calcium haemostasis. Hormones related to calcium metabolism and their effectParathormone (PTH)-Increase in PTH causes increase bone resorptionIncrease renal reabsorption of calcium, "!reabsorption of phosphatesIncrease Intestinal absorption of calcium through vitamin DOverall effect -- increased S. calcium, decreased S. phosphate.Calcitonin-increase in calcitonin causes- Increase bone mineralization Increase renal excretion-proximal tubule Decrease bone resorptionVitamin D-increased in vitamin D causes:Increase Intestinal reabsorption of calcium through Calbindin D 28K.Increase bone resorption by osteoclastic activity Increase renal reabsorption in proximal tubule of both calcium and phosphates Overall effects-Increase in S. calcium, and increase in S. phosphatesEffects of Hormones on bonePTH - Increase osteoclast, Increase osteoblast Vitamin D - Increase osteoclast, Increase osteoblastCalcitonin - Decrease osteoclast, osteoblast no changeRememberPTH has no direct action on Intestine, but acts through vitamin D Vitamin D augments the action of PTH in kidneyRANKL is seen on the osteoblast and RANK on osteoclastOPG (osteoprotegerin) - inhibitor of RANKL Osteoblastic transducing signal - cbfal
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now