“Calcinosis universalis” is due to
Correct Answer: Idiopathic calcification
Description: Deposition of calcium and phosphates in tissues is called calcification or calcinosis. If it gets organized as in bone formation, it is called ossification. Calcinosis is commonly seen as a consequence of connective tissue disorders or metabolic abnormalities.But it can occur without any tissue injury or metabolic abnormalities. The three main types are:1. Dystrophic-associated with connective tissue disorders due to tissue change. Eg. Dermatomyositis, pseudoxanthoma elasticum or Ehlers Danlos syndrom 2.ldiopathic-not associated with any tissue change or damage. Eg. Calcinosis universalis, circumscripta oumoral calcinosis. 3. Metastaticassociated with abnormal calcium and phosphorus metabolism as in hypercalcemia or hyperphosphatemia. In this type visceral organs are more affected than the skin.eg: hypervitaminosis of vitamin d, milk alkali syndrome iadvl textbook of dermatology page 1099
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