**Core Concept**
Scabies is a skin infestation caused by the mite Sarcoptes scabiei, leading to intense itching and a pimple-like skin rash. The mites burrow into the epidermis, causing characteristic lesions.

**Why the Correct Answer is Right**
The mites burrow into the stratum corneum, the outermost layer of the epidermis, which is composed of dead, flattened skin cells held together by keratin. This layer is the primary site of mite burrowing, as it provides an ideal environment for the mites to feed and lay eggs. The stratum corneum's compact structure and dead cell composition make it an ideal substrate for the mites to create their tunnels.

**Why Each Wrong Option is Incorrect**
**Option A:** The stratum basale, also known as the stratum germinativum, is the innermost layer of the epidermis, where cell division and growth occur. It is not the primary site of scabies burrowing.
**Option B:** The stratum granulosum is a thin layer of cells located above the stratum basale, where cells undergo granulation and maturation. While it is part of the epidermis, it is not the primary site of scabies burrowing.
**Option D:** "Dennis" is not a valid anatomical term related to scabies burrowing.

**Clinical Pearl / High-Yield Fact**
Scabies is a highly contagious skin infestation that requires prompt treatment with topical or oral medications. It is essential to treat all close contacts of an infected individual to prevent re-infestation.

**✓ Correct Answer: C. Stratum corneum**