**Core Concept**
Burkitt's lymphoma is a high-grade B-cell non-Hodgkin lymphoma characterized by a specific genetic translocation involving the c-MYC gene, which plays a crucial role in cell proliferation and apoptosis. This translocation leads to the overexpression of c-MYC, resulting in uncontrolled cell growth and tumorigenesis.

**Why the Correct Answer is Right**
The correct translocation in Burkitt's lymphoma involves the long arm of chromosome 8 (8q24) and one of the immunoglobulin genes (most commonly IGH on chromosome 14, but also IGK on chromosome 2 and IGL on chromosome 22). The resulting fusion gene, t(8;14)(q24;q32), juxtaposes the c-MYC promoter with the immunoglobulin enhancer, leading to the overexpression of c-MYC and the development of Burkitt's lymphoma. This translocation is a hallmark of the disease and is present in over 80% of cases.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it does not specify the correct chromosome involved in the translocation.
**Option B:** This option is incorrect as it does not mention the c-MYC gene, which is the key driver of Burkitt's lymphoma.
**Option C:** This option is incorrect as it is not a recognized translocation associated with Burkitt's lymphoma.

**Clinical Pearl / High-Yield Fact**
Burkitt's lymphoma is a rapidly growing tumor with a high propensity for CNS involvement, and prompt treatment with chemotherapy and/or radiation is essential to prevent dissemination and improve outcomes.

**Correct Answer: D. t(8;14)(q24;q32)**