Burkholderia capacia is infrequently seen in:
## Core Concept
Burkholderia cepacia (formerly known as Pseudomonas cepacia) is a type of Gram-negative, rod-shaped bacterium that is commonly found in soil and water. It is an opportunistic pathogen that can cause infections in people with compromised immune systems or underlying lung disease.
## Why the Correct Answer is Right
Burkholderia cepacia is known to cause respiratory infections, particularly in individuals with cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). It can also cause bacteremia, particularly in patients with central venous catheters or those who are immunocompromised. The correct answer, **septicemia in neutropenic patients**, is a condition where Burkholderia cepacia can infrequently be seen, but more commonly associated with other pathogens like Pseudomonas aeruginosa.
## Why Each Wrong Option is Incorrect
* **Option A:** **Cystic fibrosis patients** - Burkholderia cepacia complex (Bcc) is frequently isolated from respiratory secretions of patients with cystic fibrosis, making it a significant concern for this population.
* **Option B:** **Nosocomial infections** - Burkholderia cepacia can cause nosocomial infections, particularly in outbreaks related to contaminated water or medical equipment, making it a relevant pathogen in hospital settings.
* **Option C:** **Contaminated medical equipment** - This bacterium can survive on moist surfaces and has been associated with outbreaks related to contaminated medical equipment, such as ventilators and humidifiers.
## Clinical Pearl / High-Yield Fact
A key point to remember is that Burkholderia cepacia complex infections are particularly concerning in cystic fibrosis patients due to their potential for causing severe lung disease and their intrinsic resistance to many antibiotics, making treatment challenging.
## Correct Answer: D.