Bullous impetigo is caused by: March 2013
## **Core Concept**
Bullous impetigo is a type of skin infection that presents with large, fluid-filled blisters. It is primarily caused by bacteria that produce exfoliative toxins, leading to the separation of skin layers. The condition is most commonly seen in children.
## **Why the Correct Answer is Right**
The correct answer, **Staphylococcus aureus**, is right because this bacterium is known to produce exfoliative toxins that cause the skin condition known as bullous impetigo. These toxins act on the skin's desmoglein 1 proteins, leading to the formation of intraepidermal blisters. **Staphylococcus aureus** is a gram-positive bacterium that can cause a range of skin infections, and its ability to produce exfoliative toxins makes it a specific cause of bullous impetigo.
## **Why Each Wrong Option is Incorrect**
- **Option A:** *Streptococcus pneumoniae* is incorrect because, while streptococci can cause skin infections, they are not typically associated with the production of exfoliative toxins or bullous impetigo.
- **Option B:** *Streptococcus pyogenes* is incorrect because, although it can cause skin infections like impetigo, the type it causes is usually non-bullous.
- **Option D:** *Streptococcus faecalis* is incorrect because it is not commonly associated with skin infections like impetigo and is more commonly found in the gastrointestinal tract.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that bullous impetigo, caused by **Staphylococcus aureus**, can sometimes be confused with staphylococcal scalded skin syndrome (SSSS). However, SSSS typically affects infants and young children and presents with widespread erythema and skin tenderness, whereas bullous impetigo presents with more localized blistering.
## **Correct Answer:** . **Staphylococcus aureus**