Buerger’s Disease is

Correct Answer: All of the above
Description: BUERGER'S DISEASE (THROMBOANGITIS OBLITERANS) → Segmental inflammatory disease, affecting small and medium sized arteries in upper and lower extremities. → Inflammatory process involves neighboring veins and nerves. → Definite relationship with smoking. Histopathology → Sharply segmental acute and chronic vasculitis of small and medium vessels with thrombosis of lumen, which may undergo organization and recanalization. → Thrombus contains microabsecess Inflammatory process extends to involve neighboring veins and nerves. With time, all three structures (artery, vein and nerve) become incased in fibrous tissue. Clinical Features (RIM) → Characterized by triad of intermittent claudication, Raynaud's phenomenon and migratory superficial vein thrombophlebitis. Typically seen in young (<40 years), male smokers.
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