Buerger’s disease affects all except:-
**Core Concept**
Buerger's disease, also known as thromboangiitis obliterans, is a rare disorder characterized by inflammation and clotting of blood vessels, typically affecting the arteries and veins of the legs and arms. This condition is most commonly seen in young male smokers.
**Why the Correct Answer is Right**
The pathophysiology of Buerger's disease involves the formation of thrombi (blood clots) and subsequent inflammation of the blood vessels, leading to occlusion of the vessels and tissue ischemia. The exact cause is unknown, but smoking is a significant risk factor. The disease primarily affects the small and medium-sized vessels, leading to symptoms such as claudication, pain, and ischemic ulcers.
**Why Each Wrong Option is Incorrect**
* **Option A:** Not provided
* **Option B:** Not provided
* **Option C:** Not provided
* **Option D:** Not provided
**Clinical Pearl / High-Yield Fact**
Buerger's disease is often associated with an increased risk of heart attack and stroke, likely due to the systemic nature of the disease process. It's essential to identify and manage the underlying risk factors, particularly smoking, to prevent disease progression.
**Correct Answer:** A.