**Question:** True statement regarding Sarcoidosis is all except:

A. It is a malignant tumor.
B. It affects only the lungs.
C. It is caused by infection.
D. It is a genetic disorder.

**Core Concept:** Sarcoidosis is a chronic inflammatory disorder characterized by the formation of non-caseating granulomas in various organs. These granulomas are formed in response to unknown triggers, potentially involving genetic, environmental, or immunological factors. Sarcoidosis can affect multiple organs, including the lungs, lymph nodes, skin, eyes, heart, and liver, among others.

**Why the Correct Answer is Right:** Sarcoidosis is not a malignant tumor, as it is not related to uncontrolled cell division or cancer formation. Sarcoidosis is a chronic inflammatory disease, not a neoplastic process.

**Why Each Wrong Option is Incorrect:**

A. Sarcoidosis is a non-malignant inflammatory disorder, not a malignant tumor.
B. Although sarcoidosis can affect the lungs, it is not limited to the lungs only. It can involve various organs and systems.
C. Sarcoidosis is not caused by a single infectious agent, but by an unknown trigger that involves a complex interplay between genetic, environmental, and immunological factors.
D. Sarcoidosis is not a genetic disorder; rather, it is a multifactorial disease influenced by genetic and environmental factors.

**Clinical Pearl / High-Yield Fact:** Sarcoidosis is a challenging diagnosis to make due to its diverse presentation and potential overlap with other conditions. A thorough clinical examination, imaging studies, and occasionally biopsy are required to confirm the diagnosis. Treatment options include corticosteroids, immunosuppressants, and occasionally cytotoxic agents, depending on the extent and severity of the disease. Monitoring the disease progression and adjusting treatment accordingly is crucial for optimal management.