All of the following can be seen in bone marrow of myelodysplastic syndrome (MDS) cases, except:
💡 Explanation
## **Core Concept**
Myelodysplastic syndromes (MDS) are a group of disorders caused by poorly formed or dysfunctional blood cells, typically leading to various forms of cytopenia. The bone marrow in MDS often shows dysplasia, which can affect one or more cell lineages. Key features in the bone marrow include abnormal cell morphology, ineffective hematopoiesis, and an increased risk of progression to acute myeloid leukemia (AML).
## **Why the Correct Answer is Right**
The correct answer, , represents a feature not typically associated with MDS. In MDS, common findings in the bone marrow include:
- Dysplastic changes in erythroblasts, megakaryocytes, and granulocytes.
- Increased blasts, but not to the extent seen in AML (typically 20%
✓ Correct Answer: B. Cloud-like megakaryocytes