**Core Concept**
The liver receives a dual blood supply from the hepatic artery and the portal vein, which is unique compared to other organs. This dual blood supply is crucial for its function, as it allows for the detoxification of blood and the metabolism of nutrients.
**Why the Correct Answer is Right**
The hepatic artery supplies oxygenated blood from the aorta, while the portal vein brings nutrient-rich blood from the intestines. The combined blood flow to the liver is approximately 1500 ml/min, which is divided between the hepatic artery (25%) and the portal vein (75%). This unique blood supply arrangement allows for the efficient detoxification of blood and the metabolism of nutrients.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is too low and does not accurately reflect the combined blood flow to the liver.
**Option B:** This option is too high and exceeds the estimated combined blood flow to the liver.
**Option C:** This option is not accurate and does not reflect the correct percentage distribution between the hepatic artery and portal vein.
**Clinical Pearl / High-Yield Fact**
The liver's dual blood supply allows it to function efficiently in both the fasting and feeding states, making it a vital organ for maintaining homeostasis in the body.
**Correct Answer: D. 1500**
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