## Core Concept
The liver receives a dual blood supply from the **hepatic artery** and the **portal vein**. The hepatic artery provides oxygenated blood, while the portal vein brings nutrient-rich, deoxygenated blood from the gastrointestinal tract.

## Why the Correct Answer is Right
The liver's blood supply is unique, with a total blood flow of approximately **1500 ml/min**. This is roughly **25% of the cardiac output**. The hepatic artery supplies about **30-40%** of this blood (around 500 ml/min), and the portal vein supplies the remaining **60-70%** (around 1000 ml/min). This dual supply allows the liver to perform its critical functions, including detoxification, metabolism, and production of bile and proteins.

## Why Each Wrong Option is Incorrect
* **Option A:** 500 ml/min - This is incorrect because it represents only the blood supply from the hepatic artery, not the total liver blood flow.
* **Option B:** 1000 ml/min - This option is incorrect because it represents approximately the blood flow from the portal vein, not the total liver blood flow.
* **Option D:** 2500 ml/min - This is too high and does not accurately reflect the liver's blood supply.

## Clinical Pearl / High-Yield Fact
A key point to remember is that the liver's dual blood supply makes it highly susceptible to damage from decreased blood flow (ischemia) and allows it to metabolize a wide range of substances. Clinically, this is relevant in conditions like **hepatic artery thrombosis** or **portal vein thrombosis**, which can have significant implications for liver function.

## Correct Answer Line
**Correct Answer: C. 1500 ml/min.**