**Core Concept**
Beckwith-Wiedemann Syndrome (BWS) is a congenital overgrowth disorder characterized by macroglossia, visceromegaly, and an increased risk of embryonal tumors, including Wilms tumor. The condition is often associated with an abnormality in the imprinted genes on chromosome 11p15.5, leading to overexpression of insulin-like growth factor 2 (IGF2).

**Why the Correct Answer is Right**
The clinical presentation of this newborn, including microcephaly, macroglossia, visceromegaly, and hypoglycemia, is consistent with Beckwith-Wiedemann Syndrome. The presence of macroglossia and visceromegaly is a hallmark of the condition, and the hypoglycemia may be due to the overexpression of IGF2, leading to excessive insulin production. The abnormality in chromosome 11p15.5 is a key feature of BWS, which is associated with an increased risk of embryonal tumors.

**Why Each Wrong Option is Incorrect**
**Option A:** Prader-Willi syndrome is characterized by hypotonia, feeding difficulties, and hyperphagia leading to obesity, which does not match the clinical presentation of this newborn.

**Option C:** Werner syndrome is a rare genetic disorder that affects the aging process, but it does not present with the characteristic features of macroglossia and visceromegaly seen in this patient.

**Option D:** Cockayne syndrome is a rare disorder characterized by growth failure, progressive neurodegeneration, and photosensitivity, which does not match the clinical presentation of this newborn.

**Clinical Pearl / High-Yield Fact**
Beckwith-Wiedemann Syndrome is associated with an increased risk of embryonal tumors, including Wilms tumor, and therefore, a thorough evaluation for these tumors is essential in affected patients.

**✓ Correct Answer:** B. Beckwith–Wiedman syndrome