**Core Concept**
Blood flow to resting skeletal muscle is maintained at a relatively constant level despite changes in muscle activity. This is achieved through the autoregulatory mechanisms of the muscle, which ensure that oxygen and nutrient delivery remains adequate to meet the metabolic demands of the tissue.

**Why the Correct Answer is Right**
The primary mechanism of autoregulation in skeletal muscle involves the release of vasodilatory substances such as adenosine and prostaglandins from the muscle cells. These substances cause local vasodilation, which increases blood flow to the muscle. Additionally, the myogenic response of smooth muscle cells in the blood vessels of the muscle also contributes to autoregulation, as these cells contract in response to increased pressure, reducing blood flow. In resting skeletal muscle, the balance between these mechanisms maintains a stable blood flow.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately describe the blood flow to resting skeletal muscle. Blood flow to resting muscle is not significantly reduced.
**Option B:** This option is incorrect because it implies that blood flow to resting skeletal muscle is not maintained at a constant level, which contradicts the autoregulatory mechanisms in place.
**Option C:** This option is incorrect because it is not specific to resting skeletal muscle, and blood flow to other muscle groups may vary depending on activity level.

**Clinical Pearl / High-Yield Fact**
In clinical practice, it's essential to remember that autoregulation of blood flow in skeletal muscle can be impaired in conditions such as diabetes, where muscle blood flow may be reduced due to neuropathy and vasculopathy.

**Correct Answer: D**