**Core Concept**
The National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS) also known as the National Non-Communicable Disease (NCD) Programme, was launched by the Government of India in 2010. The NMEP (National Leprosy Eradication Programme) is a part of this initiative. The NMEP aims to eliminate leprosy as a public health problem by reducing the prevalence rate to less than 1 case per 10,000 population at the national level.

**Why the Correct Answer is Right**
The minimum annual blood examination rate for leprosy is crucial in detecting new cases and ensuring proper treatment. Leprosy is a bacterial infection caused by *Mycobacterium leprae*. Early detection and treatment can prevent disability and complications. The correct answer is based on the World Health Organization's (WHO) recommendation for leprosy control. Leprosy is diagnosed through clinical examination and bacteriological examination of skin smears.

**Why Each Wrong Option is Incorrect**
**Option A:** This is not the correct minimum annual blood examination rate as per the NMEP guidelines.
**Option B:** This is not the correct minimum annual blood examination rate as per the NMEP guidelines.
**Option D:** This is not the correct minimum annual blood examination rate as per the NMEP guidelines.

**Clinical Pearl / High-Yield Fact**
It is essential to note that the NMEP guidelines also recommend regular surveillance and reporting of leprosy cases to ensure effective control measures.

**Correct Answer:** 100. 100 cases per 100,000 population.