Pharmacology Blockade of nerve conduction by a local anaesthetic is characterized by: A Greater potential to block a resting nerve as compared to a stimulated nerve B Need to cross the cell membrane to produce the block C Large myelinated fibers are blocked before the unmyelinated fibers D Cause consistent change of resting membrane potential 💡 Explanation Blockade of nerve conduction by a local anaesthetic is characterized by: ✓ Correct Answer: B. Need to cross the cell membrane to produce the block