**Core Concept**
Beta thalassemia major, also known as Cooley's anemia, is a severe form of thalassemia that requires regular blood transfusions to manage the condition. However, these transfusions lead to iron overload in the body, which can cause organ damage and other complications. Chelation therapy is used to remove excess iron from the body.

**Why the Correct Answer is Right**
Deferiprone is an oral iron chelator that is specifically used to treat iron overload in patients with beta thalassemia major. It works by binding to iron and forming a stable complex that is excreted in the urine. Deferiprone has been shown to be effective in reducing liver iron concentrations and improving the quality of life for patients with beta thalassemia major. It is also considered a first-line treatment for iron overload in this population.

**Why Each Wrong Option is Incorrect**
**Option A:** Oral desferrioxamine is not a commonly used form of desferrioxamine, which is typically administered subcutaneously or intravenously due to its poor oral bioavailability.

**Option C:** Intramuscular EDTA is not used for iron chelation, as it is more commonly used for lead poisoning.

**Option D:** Oral Succimer is used for lead poisoning, not iron chelation.

**Clinical Pearl / High-Yield Fact**
It's essential to note that deferiprone is not without side effects, and patients on this medication require regular monitoring of liver function and blood counts. Additionally, deferiprone can interact with other medications, such as warfarin, and patients should be advised to avoid these interactions.

**✓ Correct Answer: B. Oral deferiprone**