**Core Concept**
The management of angina in a patient with hypertension requires a drug that effectively reduces myocardial oxygen demand while controlling blood pressure. This can be achieved by using a combination of drugs that act on the cardiovascular system, such as beta-blockers, calcium channel blockers, or nitrates.

**Why the Correct Answer is Right**
The best drug for angina with hypertension is **Nebivolol**, a beta-1 selective adrenergic receptor blocker. Nebivolol has a unique mechanism of action that not only reduces myocardial oxygen demand but also has vasodilatory properties, which help to reduce blood pressure. It also has antioxidant properties that help to reduce oxidative stress and inflammation in the cardiovascular system. Nebivolol's selective action on beta-1 receptors minimizes the negative effects on beta-2 receptors, which are responsible for vasodilation in the peripheral circulation.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is not specified, but common beta-blockers like Metoprolol or Atenolol may not be the best choice for hypertension due to their potential to worsen peripheral resistance and increase the risk of diabetes.

**Option B:** Calcium channel blockers like Amlodipine may be effective in reducing blood pressure, but they can worsen angina in some patients by reducing coronary artery vasodilation.

**Option C:** Nitrates like Nitroglycerin are effective in reducing angina by vasodilating coronary arteries, but they can cause a reflex increase in sympathetic tone, which can worsen hypertension.

**Clinical Pearl / High-Yield Fact**
Nebivolol's unique combination of beta-1 selectivity, vasodilatory properties, and antioxidant effects make it an ideal choice for managing angina in patients with hypertension.

**Correct Answer:** C. Amlodipine