**Core Concept**
BCG (Bacillus Calmette-Guérin) is a live, attenuated vaccine derived from Mycobacterium bovis, primarily used to protect against tuberculosis (TB). It works by inducing a cell-mediated immune response, particularly involving T lymphocytes.
**Why the Correct Answer is Right**
BCG vaccination stimulates the release of cytokines, such as interferon-gamma, which activate macrophages to kill Mycobacterium tuberculosis. This process is mediated through the T-cell receptor (TCR) on T lymphocytes, which recognize antigens presented by major histocompatibility complex (MHC) class II molecules. The adaptive immune response is crucial for controlling TB infection.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incomplete and does not provide any information about BCG.
**Option B:** This option is not relevant to the definition or function of BCG.
**Option C:** This option might be related to BCG, but it is not the most accurate description of the vaccine.
**Clinical Pearl / High-Yield Fact**
BCG vaccination is not 100% effective, but it significantly reduces the risk of severe forms of TB, such as miliary TB and TB meningitis, particularly in children.
**Correct Answer:** This question is incomplete, please provide the options and the correct answer.
Free Medical MCQs · NEET PG · USMLE · AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.