Biochemistry Base substitution mutations can have the following molecular consequence, EXCEPT: A Changes one codon for an amino acid into another codon for that same amino acid B Codon for one amino acid is changed into a codon of another amino acid C Reading frame changes downstream to the mutation site D Codon for one amino acid is changed into a translation termination codon 💡 Explanation Base substitution mutations can have the following molecular consequence, EXCEPT: ✓ Correct Answer: C. Reading frame changes downstream to the mutation site