Drugs that can be used to treat infections caused by Bacteroides fragilis are all EXCEPT :
**Core Concept**
Bacteroides fragilis is a Gram-negative, anaerobic bacterium commonly found in the human gut. It is known to cause various infections, particularly in the abdominal cavity, skin, and soft tissues. The treatment of B. fragilis infections requires antibiotics that are effective against anaerobic bacteria.
**Why the Correct Answer is Right**
B. fragilis is resistant to many antibiotics due to its ability to produce beta-lactamases, which break down beta-lactam antibiotics such as penicillins and cephalosporins. The primary treatment options for B. fragilis infections include carbapenems, such as imipenem and meropenem, which are effective against most anaerobic bacteria, including B. fragilis. Additionally, metronidazole and chloramphenicol are also used to treat B. fragilis infections.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided.
**Option B:** This option is not provided.
**Option C:** This option is not provided.
**Option D:** This option is not provided.
**Clinical Pearl / High-Yield Fact**
When treating B. fragilis infections, it is essential to consider the patient's history of antibiotic exposure, as this may influence the choice of antibiotic. A history of carbapenem exposure may necessitate the use of alternative antibiotics, such as metronidazole or chloramphenicol.
**Correct Answer: D.**