Baclofen is used in:-
Correct Answer: Spasticity
Description: GABAB (It is a G protein coupled receptor unlike GABAA, which is an ionotropic receptor) agonists like baclofen increase K+ conductance and can inhibit monosynaptic as well as polysynaptic reflexes. Baclofen is used to relieve spasticity in multiple sclerosis and spinal injuries. It is not useful in cerebral palsy.
Category:
Pharmacology
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