Bacillary angiomatosis is caused by –
**Question:** Bacillary angiomatosis is caused by -
A. Bartonella henselae
B. Bartonella quintana
C. Mycobacterium tuberculosis
D. Toxoplasma gondii
**Core Concept:** Bacillary angiomatosis is a disease characterized by the proliferation of abnormal blood vessels, usually associated with immunocompromised individuals, caused by certain bacteria.
**Why the Correct Answer is Right:** Bacillary angiomatosis is caused by Bartonella species, specifically Bartonella henselae and Bartonella quintana. These bacteria are intracellular pathogens that infect endothelial cells lining blood vessels, leading to the formation of proliferative lesions.
**Why Each Wrong Option is Incorrect:**
A. **Bartonella henselae**: Although Bartonella henselae is a common cause of bacillary angiomatosis in immunocompetent individuals, it is not the primary cause in immunocompromised patients. In these cases, Bartonella quintana is more likely.
B. **Bartonella quintana**: As mentioned above, Bartonella quintana is more likely to cause bacillary angiomatosis in immunocompromised patients.
C. **Mycobacterium tuberculosis**: Mycobacterium tuberculosis causes tuberculosis, which is a completely different disease with distinct clinical features and is not associated with angiomatosis.
D. **Toxoplasma gondii**: Toxoplasma gondii causes toxoplasmosis, another distinct infection with different clinical manifestations and is not associated with angiomatosis.
**Clinical Pearl:** Bartonella infections are important to recognize in immunocompromised patients presenting with angiomatosis-like lesions, as prompt diagnosis and appropriate treatment can prevent complications and improve outcomes.
**Correct Answer:** Bartonella quintana (Option B)
**Why Each Wrong Option is Incorrect:**
A. **Bartonella henselae**: Although Bartonella henselae is a common cause of bacillary angiomatosis in immunocompetent individuals, it is not the primary cause in immunocompromised patients. In these cases, Bartonella quintana is more likely to cause bacillary angiomatosis.
B. **Bartonella quintana**: As mentioned above, Bartonella quintana is more likely to cause bacillary angiomatosis in immunocompromised patients. Immunocompromised patients are more susceptible to Bartonella infections, and Bartonella quintana is the primary cause of bacillary angiomatosis in this population.