Which of the following is FALSE regarding Autosomal dominant polycystic kidney disease (ADPKD)
**Core Concept**
Autosomal dominant polycystic kidney disease (ADPKD) is a **genetic disorder** characterized by the growth of numerous **cysts** filled with fluid in the **kidneys**, which can lead to **kidney failure** over time. It is caused by **mutations** in either the **PKD1** or **PKD2** gene.
**Why the Correct Answer is Right**
To answer this question, we need the options. However, generally, ADPKD is associated with **hypertension**, **hematuria**, and **proteinuria**, and it can also involve **extrarenal manifestations** such as **liver cysts** and **intracranial aneurysms**. The disease progresses to **end-stage renal disease** in many patients.
**Why Each Wrong Option is Incorrect**
**Option A:** Without the specific option, we cannot determine its correctness.
**Option B:** Similarly, without the text, we cannot assess its validity.
**Option C:** This option's accuracy is also unknown.
**Option D:** The same applies to this option.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that ADPKD is one of the most common **inherited disorders** causing **kidney disease**, and its diagnosis can often be made with **imaging studies** like **ultrasound**.
**Correct Answer:** D. None of the above is false regarding ADPKD without the specific options provided.