Isoantigens are(82, 190-AN 7th) (131, 133-CP)A. Found in some but all members of speciesB. Found in some but not all members of speciesC. Occurs in different biological species, class and kingdomsD. All individuals in a particular speciesAns: BSolution: (Found in some but not all members of species) (82, 190-AN 7th) (131-133-CP)Isoantigens or Alloantigens – alloantigens or isoantigens are found to be present in some but not all members of a species which are able to produce alloantibodies or (isoantibodies) in individuals who are free from the antigensDifferent antigensGroup AntigensForeignMicrobial:Cell walls, pili, enzymes toxins. Drugs:Sedermoid. Environmental:Dust, pollens.AutoantigensSelfThyroglobulin, DNA, corneal tissueIsoantigensBlood:Blood group antigens (ABO, Rh) Tissue:HLA antigensHeteroantigens Heterophile antigens, cross reacting microbial antigensSwimming pool granuloma is caused by
Isoantigens are(82, 190-AN 7th) (131, 133-CP)A. Found in some but all members of speciesB. Found in some but not all members of speciesC. Occurs in different biological species, class and kingdomsD. All individuals in a particular speciesAns: BSolution: (Found in some but not all members of species) (82, 190-AN 7th) (131-133-CP)Isoantigens or Alloantigens – alloantigens or isoantigens are found to be present in some but not all members of a species which are able to produce alloantibodies or (isoantibodies) in individuals who are free from the antigensDifferent antigensGroup AntigensForeignMicrobial:Cell walls, pili, enzymes toxins. Drugs:Sedermoid. Environmental:Dust, pollens.AutoantigensSelfThyroglobulin, DNA, corneal tissueIsoantigensBlood:Blood group antigens (ABO, Rh) Tissue:HLA antigensHeteroantigens Heterophile antigens, cross reacting microbial antigensSwimming pool granuloma is caused by
π‘ Explanation
**Question:** Isoantigens are (82, 190-AN 7th) (131, 133-CP) A. Found in some but all members of species B. Found in some but not all members of species C. Occurs in different biological species, class, and kingdoms D. All individuals in a particular species
**Answer:** Isoantigens or alloantigens are found in some but not all members of a species, which are able to produce alloantibodies or (isoantibodies) in individuals who are free from the antigens.
**Core Concept:**
Isoantigens are a type of antigens that are found in some but not all individuals within a species. They differ from alloantigens, which are antigens found in different species. These isoantigens can trigger production of isoantibodies in individuals who are isoantigen-negative. Isoantibodies are produced in response to these antigens when an individual encounters them for the first time, usually due to blood transfusion or organ transplantation.
**Why the Correct Answer is Right:**
The correct answer is "Found in some but not all members of a species" because isoantigens are specific to certain individuals within a species but not present in the entire population. When an isoantigen-negative individual receives blood or organ from a donor with a different isoantigen type, their immune system recognizes these antigens as foreign and produces isoantibodies.
**Why Option A is Incorrect:**
Option A, "Found in all members of a species," is incorrect because not all individuals within a species possess isoantigens. This is why isoantibodies can form when a person with a specific isoantigen type receives a transfusion or transplant from a donor with a different isoantigen type.
**Why Option B is Incorrect:**
Option B, "Found in different biological species, classes, and kingdoms," is incorrect because isoantigens are specific to an individual within a species, not across different biological entities. The immune system recognizes these antigens as foreign when they are encountered for the first time, leading to the production of isoantibodies.
**Why Option C is Incorrect:**
Option C, "Occurring in different species, classes, and kingdoms," is incorrect because isoantigens are specific to individuals within the same species. Isoantibodies are produced when an individual with a specific isoantigen type receives a transfusion or transplant from a donor with a different isoantigen type.
**Why Option D is Correct:**
Option D, "Found in some but all members of a species," is correct because isoantigens are specific to certain individuals within a species. When an isoantigen-negative individual receives a transfusion or transplant from a donor with a different isoantigen type, their immune system recognizes these antigens as foreign, leading to the production of isoantibodies.
**Clinical Applications:**
Understanding isoantigens is crucial for transfusion medicine and organ transplantation. When blood or tissue from an individual with a different isoantigen type is administered to an individual with a specific isoantigen type, isoantibodies are formed against
β Correct Answer: D. M. marinum
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