**Core Concept**
Auditory toxicity refers to the damage or impairment of the auditory system, particularly the hair cells in the cochlea, caused by certain medications or substances. This condition can result in permanent hearing loss or tinnitus.
**Why the Correct Answer is Right**
The correct answer is Ototoxicity induced by Aminoglycoside antibiotics, particularly Gentamicin and Tobramycin. Aminoglycosides bind to the hair cells in the cochlea, causing damage and leading to auditory toxicity. This is due to the inhibition of protein synthesis in the hair cells, leading to cell death and ultimately, hearing loss.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify a particular class of antibiotics that are known to cause auditory toxicity. While other antibiotics may have ototoxic effects, Aminoglycosides are the most well-known and commonly associated with this condition.
**Option B:** This option is incorrect because while Loop diuretics like Furosemide can cause ototoxicity, they are not as potent or commonly associated with auditory toxicity as Aminoglycosides.
**Option C:** This option is incorrect because while certain antimalarials like Quinine have been associated with ototoxicity, they are not as commonly linked to auditory toxicity as Aminoglycosides.
**Clinical Pearl / High-Yield Fact**
Aminoglycoside-induced auditory toxicity can be minimized by monitoring serum levels, using the minimum effective dose, and avoiding concurrent use with other ototoxic agents.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.