At the end of repolarization, the nerve is hyperpolarized. How does the membrane potential return to RMP?
Correct Answer: Inward leakage of Na+
Description: Simultaneously with the action of the pump, there is inward diffusion of Na+ through the leaky channels (not the voltage-gated channels that cause depolarization). This inward leakage of positive charges will take the membrane potential from - 90 mV to original RMP of - 70 mV. Both the pump and the inward leakage will balance out once the potential again reaches - 70 mV.
Category:
Physiology
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