Medical MCQ-At low infusion rates of 3-5 mcg/kg/min, what action is produced by dopamine?

At low infusion rates of 3-5 mcg/kg/min, what action is produced by dopamine?

Vasoconstriction

Increased renal blood flow

Increased cardiac contractility

Decreased blood pressure

Question Category:

Pharmacology

Correct Answer:

Increased renal blood flow

Description:

Ans: B. Increased renal blood flow(Ref: Goodman Gilman 12/e p355; KDT 7/e p134. 6/e p507)Action of dopamine:At low concentrations (2 to 5 mcg/kg per minute):Primarily acts on vascular D1 receptors.Mainly renal, mesenteric & coronary beds.By activating adenylyl cyclase a raising intracellular cyclic AMP concentrations.D1 receptor stimulation a Vasodilation.Increases in glomerular filtration rate, renal blood flow & Nat+ K+ - ATPase pump.

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