A 35 years old mother of two children is suffering from amenorrhea for last 12 months. She has history of failure of lactation following 2nd delivery but remained asymptomatic thereafter. Skull radiography shows “Empty sella”. Most likely diagnosis is:

**Core Concept**
The empty sella turcica is a condition characterized by the herniation of the pituitary gland into the sella turcica, resulting in a depression of the sella turcica on radiographic imaging. This condition is often associated with hypothalamic-pituitary dysfunction, which can lead to various endocrine disorders.

**Why the Correct Answer is Right**
The patient's presentation of amenorrhea, failure of lactation following delivery, and radiographic evidence of an empty sella turcica are highly suggestive of Sheehan syndrome, a rare condition characterized by postpartum pituitary necrosis due to hypovolemic shock. This condition leads to a deficiency in anterior pituitary hormones, including thyroid-stimulating hormone (TSH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), growth hormone (GH), and adrenocorticotropic hormone (ACTH), resulting in symptoms such as amenorrhea, infertility, and failure of lactation.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided, but it's likely a distractor.
**Option B:** This option is not relevant to the patient's presentation and radiographic findings.
**Option C:** This option is not correct, as the patient's symptoms and radiographic evidence are more consistent with Sheehan syndrome than with a pituitary adenoma.

**Clinical Pearl / High-Yield Fact**
Sheehan syndrome is a rare but important diagnosis to consider in postpartum women presenting with amenorrhea and failure of lactation, as it can be life-threatening if left untreated. Early recognition and treatment of Sheehan syndrome are crucial to prevent long-term complications.

**Correct Answer:** C.

✓ Correct Answer: C. Sheehan's syndrome