Aspirin is contraindicated in a patient who is on treatment with:
Correct Answer: Warfarin
Description: Aspirin can displace warfarin from protein binding sites elevating the free drug level, leading to prolongation of both bleeding time and prothrombin time. So it should not be used in patients on anticoagulation therapy due to increased risk of bleeding. Other drugs which were found to increase the level of warfarin are: Azapropazone Phenylbutazone Naproxen Mefenamic acid Ibuprofen Ref: Enzyme- and Transpoer-Based Drug-Drug Interactions: Progress and Future Challenges edited by K. Sandy Pang, page 656.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now