As per RNTCP guidelines, Multi drug resistance (MDR) TB is defined as resistance to:
Correct Answer: Rifampicin and isoniazide
Description: Confirmed MDR-TB case: MDR-TB suspect is one who is sputum culture positive and whose TB is due to Mycobacterium tuberculosis that are resistant in-vitro to at least isoniazid and rifampicin (the culture and DST result being from an RNTCP accredited laboratory). Ref: Park 21st edition, page 178.
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