Area of brain resistant to neurofibrillary tangles in Alzheimer’s disease:

Correct Answer: Lateral geniculate body
Description: Histopathological studies have shown that neurofibrillary tangles are rarely present in lateral geniculate bodies Neurofibrillary tangles : These are intracellular deposits made up of Tau proteins Amount & distribution of NFTs correlates with severity , distribution of Alzheimer NFTs are found commonly in following areas: Coical neurons (esp entorhinal coex) Hippocampus Amygdala Basal forebrain Raphe nuclei
Category: Psychiatry
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